Big-dollar bets

These donations to help spur social change were last year’s most inspiring gifts—and those likeliest to succeed large fortunes beget large gifts, and more than ever, prominent philanthropists are anteing up $25 million–plus to help tackle problems of poverty, disease, substandard education and more. Boston’s Bridge­span Group found 74 such gifts in 2016, totalling $6.7 billion. Its panel of outside experts then ranked the 10 listed below as the most promising. For more, please see forbes.com/big-bets-2017.